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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX19
All Species:
31.82
Human Site:
Y218
Identified Species:
70
UniProt:
P40855
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40855
NP_001124511.1
299
32807
Y218
P
P
E
Q
F
E
K
Y
Q
E
Q
H
S
V
M
Chimpanzee
Pan troglodytes
XP_001171866
279
30701
S220
E
A
E
T
P
T
D
S
E
T
T
Q
K
A
R
Rhesus Macaque
Macaca mulatta
XP_001117501
299
32772
Y218
P
P
E
Q
F
E
K
Y
Q
E
Q
H
S
V
M
Dog
Lupus familis
XP_536130
299
32557
Y218
P
P
E
Q
F
E
K
Y
Q
E
Q
H
S
V
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCI5
299
32715
Y218
P
P
E
Q
F
E
K
Y
Q
Q
Q
H
S
V
M
Rat
Rattus norvegicus
Q9QYU1
299
32479
Y218
P
P
E
Q
F
E
K
Y
Q
Q
Q
H
S
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514260
337
36000
Y258
G
A
D
Q
L
Q
R
Y
R
Q
Q
H
H
I
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089075
286
31356
Y208
P
A
E
E
Y
N
K
Y
K
E
Q
H
K
L
M
Zebra Danio
Brachydanio rerio
NP_001017399
288
31524
Y212
P
S
D
Q
F
T
R
Y
E
Q
Q
Y
K
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609547
292
31287
Y213
S
A
E
D
K
E
R
Y
Q
K
Q
M
E
L
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34453
282
30969
F201
L
G
K
I
C
T
E
F
E
K
Q
P
E
L
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
98.6
96.3
N.A.
90.6
92.9
N.A.
56.3
N.A.
73.2
59.2
N.A.
30.1
N.A.
31.7
N.A.
Protein Similarity:
100
93.3
99
97.6
N.A.
94.3
95.6
N.A.
67.6
N.A.
84.9
75.2
N.A.
50.8
N.A.
49.8
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
33.3
N.A.
53.3
40
N.A.
33.3
N.A.
6.6
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
73.3
N.A.
80
80
N.A.
53.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
0
0
0
0
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
10
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
73
10
0
55
10
0
28
37
0
0
19
0
0
% E
% Phe:
0
0
0
0
55
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
64
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
19
0
% I
% Lys:
0
0
10
0
10
0
55
0
10
19
0
0
28
0
0
% K
% Leu:
10
0
0
0
10
0
0
0
0
0
0
0
0
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
73
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
64
46
0
0
10
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
64
0
10
0
0
55
37
91
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
28
0
10
0
0
0
0
0
10
% R
% Ser:
10
10
0
0
0
0
0
10
0
0
0
0
46
0
0
% S
% Thr:
0
0
0
10
0
28
0
0
0
10
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
82
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _